Center for Chemical Genomics
The Center for Chemical Genomics provides high-throughput screening facilities allowing researchers to assess biological target activity by testing large libraries of compounds, siRNA, and natural product extracts.
Center for Structural Biology
The Center for Structural Biology provides 3-D images from X-ray crystallography to reveal the structures of drug targets and drugs bound to targets; the lab also optimizes conditions to produce target proteins for use in research.
Protein purification, macromolecular crystallization and crystallography and x-ray: Jeanne Stuckey, firstname.lastname@example.org, 734.647.7534
High throughput protein lab: Clay Brown, email@example.com
Administrative: Rebecca Epstein, firstname.lastname@example.org, (734) 615-9317
Vahlteich Medicinal Chemistry Core
The Vahlteich Medicinal Chemistry Core designs and synthesizes small molecule compounds to optimize their biological activity and drug-like properties.
Scott Larsen, Director, email@example.com, (734) 615-0454
Hollis Showalter, Co-Director, firstname.lastname@example.org, (734) 764-5504
For information on computational tools and resources, contact Paul Kirchhoff at email@example.com.
The Pharmacokinetics Core helps to test and improve how new drugs will be absorbed by the body, distributed across different internal systems, and broken down, which will help to select best lead compounds; the lab also measures drug concentrations to support Phase I and II clinical trials for dose optimization.
Duxin Sun, Director, firstname.lastname@example.org, (734) 615-8740
Bo Wen, Core Manager, email@example.com, (734) 615-3470