ANN ARBOR—The University of Michigan Center for the Discovery of New Medicines has awarded early-stage funding for seven new drug discovery projects by faculty from across U-M.

Six of the projects focus on treating disease including heart failure, runaway cell division in cancer, hypertension, Crohn’s disease, a genetic heart disorder and neurological damage. A seventh project aims to improve agents used in positron emission tomography, or PET scanning, which doctors use to evaluate...


Patients with Chronic Kidney Disease (CKD) may benefit from a new collaboration between the University of Michigan (U-M) and AstraZeneca who have partnered to develop a new therapeutic strategy for treatment. The partners will jointly conduct chemistry and drug discovery research with the aim of developing candidate drugs.

The four-year collaboration, led by U-M nephrologist Matthias Kretzler, M.D. and Vince Groppi, Ph.D. from the Center for Discovery of New Medicines at U-M, brings...


ANN ARBOR — The University of Michigan Center for the Discovery of New Medicines has awarded funding for four new drug discovery projects by U-M faculty aimed at fighting cancer, sickle cell disease and creating new, non-addictive painkillers.

For the first time, the center is also providing formal mentoring support to two promising, early-stage cancer drug discovery projects, which it hopes to further support in the future with grant funding.

“These projects are great examples...


Vincent GroppiANN ARBOR—Vincent Groppi, a leader in pharmaceuticals and biotechnology, has assumed the position of director of the University of Michigan’s Center for the Discovery of New Medicines.

The CDNM is a virtual center that supports early-stage, innovative drug-discovery research projects across the university and is...